Less Back pain, better quality of life
Low back pain is a chronic lower back problem, which negatively impacts the quality of life of sufferers and the people around them, it is also one of the most common conditions of constant pain and sometimes permanent that occurs most often in people 30 to 50 years of age, generated by factors such as age, the natural process of wear and aging, lifestyles, and on many occasions, including unknown factors.
Low back pain is severe or moderate pain, which occurs sometimes in other acute and chronic type. In the first, the origin is usually caused by muscle strains and sprains from handling heavy objects, exercising with weights or bad posture. Chronic low back pain most often associated with poor posture, improper footwear and overweight.
Among the relatively few health care options available to such conditions, NSAIDs are also called NSAIDs, and new generation drugs called coxibs or COX-2, a substance responsible for triggering inflammation and pain.
While both classes of drugs inhibit production of COX-2, NSAIDs also prevent the secretion of COX-1, a substance which, among other things, favors the generation of protective elements of the stomach.
In the largest study of treatment of chronic low back pain with NSAIDs done so far, in 24 countries and published in the twentieth issue of Current Medical Research and Opinion, we sought to expand the clinical database on the use of these drugs in the treatment of chronic low back pain.
This study showed that a daily dose of etoricoxib, a coxib, provided rapid pain relief and significant improvement in patient mobility, the four hours of ingesting the drug, results comparable to the prescription of high doses of diclofenac (a traditional NSAID use) three times a day.
This study was double-blind, randomized, four weeks and involved 446 patients aged 19 to 85 years in 62 centers in 24 countries in Europe, America, Asia and Australia. Design had a "relapse", ie, patients were eligible to participate if their symptoms worsened after discontinuation of treatment for almost a week.